Pancramin - peptide bioregulator of pancreas

For pancreatitis, gastrointestinal disorders and type 2 diabetes

Recommended to improve the functioning of the pancreas, normalizes digestion and metabolic processes in the body.

Indications

Pancramin is indicated for various disorders of pancreatic function, such as:

• Acute pancreatitis
• Chronic pancreatitis
• Non-insulin dependent diabetes
• Gastrointestinal diseases with metabolic disorders
• Pre- and postoperative period in operations on the gastrointestinal tract, pancreas and duodenum
• Old age (to maintain normal function of the digestive system)
• For elderly people to maintain the activity of pancreatic cells

The pancreas, located behind the stomach, is 15-20 centimeters long and weighs only 50-70 grams. However, the importance of this organ in digestion and metabolism of the body as a whole is difficult to overestimate. Firstly, the pancreas produces pancreatic juice, which consists of three main enzymes: lipase (helps break down fats), amylase (responsible for carbohydrates), chymotrypsin and trypsin (break down proteins). Secondly, the pancreas secretes insulin, glucagon and other hormones, which, entering the blood, normalize glucose metabolism. If this system fails, a terrible disease occurs - diabetes. 

Damage to pancreatic cells can be caused by many factors:

• An infectious factor (viruses and bacteria) that causes inflammation of the pancreas (pancreatitis);
• Toxic factors (such as alcohol consumption) also destroy pancreatic cells;
• Long-term increase in blood glucose levels;
• Autoimmune disorders and more.  

How to restore pancreatic cells when they are damaged? 

Of course, it depends on the mechanism and type of damage, which requires a special approach in each specific case. However, it can be said in general - almost all types of damage affect the protein structure of cells. This was established thanks to the discovery made in 1999 by Gunter Blobel, who received the Nobel Prize for his scientific work. The scientist found out that the protein molecule is self-regulating. Deficiency of proteins, peptides (with age or with damaging factors) accelerates tissue wear, aging processes and leads to the development of diseases.

In order for cells to regenerate and be protected from damage, they primarily need proteins. But each type of tissue contains specific types of proteins.

How does Pancramin work?

The components for Pancramin, obtained from enzyme-endocrine raw materials, do not contain insulin and are represented by a complex of proteins and nucleoproteins that have a specific, selective effect on the cellular structures of the human pancreas. The whole point is that the complexes of proteins and nucleoproteins are identical in all mammals. Due to this, Pancramin promotes the activation of restorative processes in the gland tissue and normalizes its digestive and hormonal functions.

Like all cytomins, due to the mechanism of transcytosis, Pancramin acts specifically on the cells of the pancreas and helps to normalize their function.

Thanks to the mechanism of transcytosis, the incoming protein in an unchanged form ends up in the target cell. In this case, the target is the cells of the pancreas - pancreocytes. Getting into them, Pancramin saturates them with an optimal protein "diet", allowing the cells to recover faster and normalize the performance of their functions - the secretion of insulin and enzymes for normal digestion. 

Clinical trials of Pancramin were conducted on 125 patients with chronic pancreatitis and latent type 1 diabetes mellitus.

During the course of Pancramin use in patients with chronic pancreatitis, appetite increased, the frequency of dyspeptic disorders decreased, and general well-being improved. An increase in the activity of pancreatic enzymes (trypsin and amylase) was observed, which corresponded to positive clinical dynamics.

In patients with latent diabetes mellitus, Pancramin was used under the control of a glucose tolerance test, and it was found that while taking Pancramin, there was a gradual decrease in blood glucose levels followed by their normalization.

Pancramin is recommended to be taken 1-3 tablets 10-15 minutes before meals 2-3 times a day for 10-15 days. Repeat the course after 3-6 months. Pancramin has no contraindications and can be used both independently and as part of complex therapy.

Active ingredient:  a complex of proteins and nucleoproteins isolated from the pancreas of cattle